SUBTOTAL RESECTION OF BONE TO THE ZONE OF METAEPIPHYSIS IN CHILDREN WITH MALIGNANT NEOPLASMS
Keywords:
osteogenic sarcoma, Ewing sarcoma, autoplasty bones, autoclaved bone, vascularized fibula, functional outcome.Abstract
Summary. Objective: to analyze the effectiveness subtotal
resection of bone in children with malignant tumors, using autoplasty defect autoclaved and vascularized fibula
bone lesions in advanced tumor to metaepiphysis zone.
Subjects and methods: for period from September 2010
for October 2015 8 children (4 girls, 4 boys) were operated
in age from 9 to 14 with malignant bones tumors, the extent of defeat was about ⅔ of the bone length. Results: no
local recurrence of the tumor was noted at time of observation from 4 to 54 months. Functional outcome according
to Musculoskeletal Tumor Society was 90.0 ± 8.5%.
References
Grimer RJ. Surgical options for children with osteosarcoma. Lancet Oncol 2005; 6 (2): 85–92.
Bacci G, Ferrari S, Mercuri M, et al. Predictive factors for
local recurrence in osteosarcoma: 540 patients with extremity tumors followed for minimum 2.5 years after neoadjuvant chemotherapy. Acta Orthop Scand 1998; 69 (3): 230–6.
Dae-Geun Jeon,Won Seok Song, Chang-Bae Kong, et al.Role
of surgical margin on local recurrence in high risk extremity osteosarcoma: a case-controlled study. Clin Orthop Surg 2013; 5 (3): 216–24.
Loh AH, Navid F, Wang C, et al. Management of local recurrence of pediatric osteosarcoma following limb-sparing surgery.
Ann Surg Oncol 2014; 21 (6): 1948–55.
Jing Li, Zhen Wang, Zheng Guo, et al. Irregular osteotomy
in limb salvage for juxta-articular osteosarcoma under computerassisted navigation. J Surg Oncol 2012; 106 (4): 411–6.
Bertrand TE, Cruz A,Binitie O, et al. Do surgical margins affect local recurrence and survival in extremity, nonmetastatic, highgrade osteosarcoma? Clin Orthop Relat Res 2016; 474 (3): 677–83.
Malawer MM, Chou LB. Prosthetic survival and clinical results with use of large-segment replacements in the treatment of
high-grade bone sarcomas. J Bone Joint Surg 1995; 77A: 1154–6.
Santacreu E, de Sotos J, Delgado E. Result of allografts after cancer surgery in children. J Bone Joint Surg Br 2010; 92 (Supp1): 81–8.
Laffosse JM, Accadbled F, Abid A, et al. Reconstruction of
long bone defects with a vascularized fibular graft after tumor resection in children and adolescents: thirteen cases with 50-month followup. Rev Chir Orthop Reparatrice Appar Mot 2007; 93 (6): 555–63.
Capanna R, Bufalini C, Campanacci M. A new technique
for reconstructions of large metadiaphyseal bone defects. A combined graft (Allograft shell plus vascularized fibula). Orthopedics
Traumatol 1993; 2 (3): 159–77.
Enneking W, Dunham W, Gebhardt M. A system for the
functional evaluation of reconstructive procedures after surgical
treatment of tumors of the musculoskeletal system. Clin Orthop
Relat Res 1993; 286: 241–6.
KokL, WaiH, GekB, et al.Limb salvage in osteosarcoma using
autoclaved tumor-bearing bone.World J Surg Oncol2012; 10: 105–15.
