CERVICAL CANCER IN PREGNANCY: A MODERN GUIDELINE AND A VECTOR FOR THE DEVELOPMENT OF THERAPEUTIC APPROACHES

Abstract

Over the past quarter-century, there has been a trend of the late birth of children. Today 22% of women in Europe are over 35 at the time of first birth. The Pan-European trend, unfortunately, has embraced Ukraine. As the cancer incidence increases with age, the number of women diagnosed with cancer during pregnancy increa­ses. One of the most frequently diagnosed gynecological cancers in pregnancy is cervical cancer. The frequency of cervical cancer during pregnancy according to world national cancer registries is 1.8–4.0/100,000 pregnancies. There is no similar statistics in Ukraine, but the increasing frequency of referring such patients to the National Cancer Institute indicates the relevance of this problem for our country. The lecture was analyzed current approaches to the diagnosis and treatment of cervical cancer at different terms of pregnancy, approved by the Euro­pean Society of Gynecological Oncology (ESGO) and The International Network on Cancer, Infertility and Pregnancy (INCIP). Pregnancy, mother’s illness, toxicity of treatment, and choice of intervention time are factors that affect early postnatal and long-term results in children born to women who have been diagnosed with cervical cancer during pregnancy. The complexities that arise in the planning and treatment of patients with this pathology during pregnancy require the work of a multidisciplinary team consisting of a neonatologist, an oncogynecologist, an obstetrician, a teratologist, a toxicologist, and also need psychological support, both during the entire pregnancy and in the postpartum period.