ІНТРАПЕРИТОНЕАЛЬНИЙ МЕТАСТАТИЧНИЙ КАСКАД: МОЛЕКУЛЯРНІ ТА КЛІТИННІ ЧИННИКИ, МЕХАНІЗМИ
Ключові слова:
карциноматоз очеревини, інтраперитонеальний метастатичний каскад, пухлинне мікрооточення, мезотелій.Анотація
Проведено аналітичний огляд сучасної наукової інформації щодо чинників, механізмів, етапів ураження черевної порожнини клітинами злоякісних пухлин травного тракту і геніталій. Злоякісна пухлина є складною динамічною мікрофізіологічною системою, що тісно пов’язана з організмом,
в якому розвивається. Реалізація процесів імплантаційного метастазування потребує активації багатьох клітин організму хворого. Здійснення
усіх етапів інтраперитонеального метастатичного каскаду відбувається на тлі постійного взаємовпливу пухлинних клітин і всіх елементів пухлинного мікрооточення.
Посилання
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