ПЕРСПЕКТИВИ ЗАСТОСУВАННЯ ФІТОЕСТРОГЕНІВ У ПРОФІЛАКТИЦІ ЗЛОЯКІСНИХ НОВОУТВОРЕНЬ ТА ПРОТИПУХЛИННІЙ ТЕРАПІЇ
DOI:
https://doi.org/10.32471/oncology.2663-7928.t-23-4-2021-g.10016Ключові слова:
ізолят соєвого білка, протипухлинна терапія, профилактика, рак, рецептори естрогенів, фітоестрогениАнотація
Cтаття присвячена аналізу даних наукової літератури та висвітленню власних результатів щодо можливості і перспектив використання біологічно активних компонентів соєвих продуктів з метою профілактики злоякісних пухлин, у схемах комбінованого лікування пацієнтів онкологічного профілю, а також у якості препаратів супроводу. Судячи з даних, що накопичені в процесі інтенсивних досліджень, фітоестрогени та інші складові соєвих продуктів регулюють цілий ряд механізмів, що беруть участь у процесах проліферації клітин, регуляції клітинного циклу, апоптозі, ангіогенезі та метастазуванні пухлинних клітин. Епідеміологічні та експериментальні дані показують, що наявність соєвих продуктів у раціоні може бути ефективним чинником профілактики раку або гальмування пухлинного процесу. Наведені дані обґрунтовують можливість і перспективність застосування біологічно активних речовин соєвих продуктів у харчуванні практично здорових людей, а також у якості компонентів протипухлинної терапії і препаратів супроводу.
Посилання
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