Comparative physical chemical stability of composition systems of hydroxyapatite/polyethyleneglycol 400 and 6000 in biological media

Authors

  • N.V. Boshytska Frantsevich Institute for Problems of Material Sciences of the NAS of Ukraine, Kiev
  • L.S. Protsenko Frantsevich Institute for Problems of Material Sciences of the NAS of Ukraine, Kiev
  • O.N. Budilina Frantsevich Institute for Problems of Material Sciences of the NAS of Ukraine, Kiev
  • N.V. Kaplunenko Frantsevich Institute for Problems of Material Sciences of the NAS of Ukraine, Kiev
  • I.V. Uvarova Frantsevich Institute for Problems of Material Sciences of the NAS of Ukraine, Kiev

DOI:

https://doi.org/10.15407/dopovidi2017.08.043

Keywords:

chemical stability, hydroxyapatite, physiological solution, polyethylene glycol, surface

Abstract

Interaction of composite systems on the bases of hydroxyapatite and polyethylene glycol (HAP + PEG) with molecular weights of 400 and 6000 with physiological Ringer and Ringer-Locke solution of NaCl has been investigated. By the methods of chemical analysis, it is established that the HAP + PEG 400 composite system interacts with biological media liberating calcium from a material step-by-step. The powder HAP + PEG 6000 system remains chemically stable during 100 h. By IR-spectroscopy, it is demonstrated that the spectrogram of surfaces of HAP + PEG 400 and HAP + PEG 6000 samples after the interaction with physiological solutions during 100 h contains valence vibrations in a range corresponding to the PEG presence. It can be supposed that the chemical activity of HAP + PEG 400 material relative to calcium and the prolonged presence of polyethylene glycol in the biological media help a reduction in both mineral metabolism and nervous impulses at bone defects. It is shown that the composite HAP + PEG 400 system is promising for the future development of materials for orthopedic applications.

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References

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Published

15.09.2024

How to Cite

Boshytska, N., Protsenko, L., Budilina, O., Kaplunenko, N., & Uvarova, I. (2024). Comparative physical chemical stability of composition systems of hydroxyapatite/polyethyleneglycol 400 and 6000 in biological media . Reports of the National Academy of Sciences of Ukraine, (8), 43–50. https://doi.org/10.15407/dopovidi2017.08.043

Issue

No. 8 (2017): Reports of the National Academy of Sciences of Ukraine

Section

Materials Science

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