8-(Methyl sulfo nyl)-2,6-dihydroimidazo[1,2-c]pyrimidine-5- (3H)-ones — new heterocyclic derivatives of sulfones with antiviral activity
DOI:
https://doi.org/10.15407/dopovidi2019.05.075Keywords:
2-c]pyrimidine- 5(3H)-one, 3-amino-2-(methylsulfonyl)acrylonitrile, 6-dihydroimidazo[1, 8-(methylsulfonyl)-2, antiviral activity, heterocyclylizationAbstract
By the interaction of 3-(R-amino)-2-(methylsulfonyl)acrylonitrile and 1-isocyanate-2-chloroethane, new sulfonе analogues of cytosine, 8-(methylsulfonyl)-6-R-2,6-dihydroimidazo[1,2-c]pyrimidine-5(3H)-ones, are synthesized. The antiviral activity of 8-(methylsulfonyl)-6-benzyl-2,6-dihydroimidazo[1,2-c]pyrimidine-5(3H)-one has been proven.
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