Effects of CdS quantum dots synthesized by various biological systems on cancer cells

Authors

  • T. V. Nikolaienko ESC “Institute of Biology”, Taras Shevchenko National University of Kiev
  • V. V. Nikulina ESC “Institute of Biology”, Taras Shevchenko National University of Kiev
  • N. A. Petruk ESC “Institute of Biology”, Taras Shevchenko National University of Kiev
  • A. I. Prysyazhnyuk ESC “Institute of Biology”, Taras Shevchenko National University of Kiev
  • O. V. Scachkova National Cancer Institute, Kiev
  • M. N. Borovaya Institute of Food Biotechnology and Genomics of the NAS of Ukraine, Kiev
  • Ya. V. Pirko Institute of Food Biotechnology and Genomics of the NAS of Ukraine, Kiev
  • L. V. Garmanchuk ESC “Institute of Biology”, Taras Shevchenko National University of Kiev
  • G. M. Tolstanova ESC “Institute of Biology”, Taras Shevchenko National University of Kiev
  • A. I. Yemets Institute of Food Biotechnology and Genomics of the NAS of Ukraine, Kiev

DOI:

https://doi.org/10.15407/dopovidi2016.05.117

Keywords:

quantum dots CdS, Escherichia coli, Pleurotus ostreatus, Linaria maroccanа, HeLa

Abstract

Three types of semiconductor CdS nanoparticles (quantum dots) are obtained by biosynthesis, using bacteria Escherichia coli, the fungus Pleurotus ostreatus, and the plant — Linaria maroccana. The effects of CdS quantum dots on the cancer cell line HeLa is studied. All types of CdS quantum dots vs ionic Cd2+ have weaker cytotoxic and cytostatic activities. The effects on cells’ adhesive potential depend on the types of CdS quantum dots. The least toxic quantum dots are synthesized, using the fungus Pleurotus ostreatus. Low toxic effects of studied fluorescent CdS nanoparticles on cancer cells might promise their effective application to cell biology and biomedical research.

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Published

27.10.2024

How to Cite

Nikolaienko, T. V., Nikulina, V. V., Petruk, N. A., Prysyazhnyuk, A. I., Scachkova, O. V., Borovaya, M. N., Pirko, Y. V., Garmanchuk, L. V., Tolstanova, G. M., & Yemets, A. I. (2024). Effects of CdS quantum dots synthesized by various biological systems on cancer cells. Reports of the National Academy of Sciences of Ukraine, (5), 117–125. https://doi.org/10.15407/dopovidi2016.05.117

Issue

No. 5 (2016): Reports of the National Academy of Sciences of Ukraine

Section

Biochemistry

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