Myeloprotective Effect of Combined Application of Ukrainian-Made Recombinant Granulocyte Colony Stimulating Factor (R-GCSF) and С2 Enterosorbent in Rats with Malignant Guerin Carcinoma

Authors

  • I.M. Todor R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, the NAS of Ukraine, Kyiv
  • N.Yu. Lukianova R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, the NAS of Ukraine, Kyiv
  • N.K. Rodionova R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, the NAS of Ukraine, Kyiv
  • O.O. Shevchuk I.Ya. Horbachevsky Ternopil State Medical University, the MHC of Ukraine, Ternopil
  • V.G. Nikolaev R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, the NAS of Ukraine, Kyiv
  • V.F. Chekhun R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, the NAS of Ukraine, Kyiv

DOI:

https://doi.org/10.15407/scine11.02.043

Keywords:

enterosorption, granulocyte colony stimulating factor, myelosupression, tumor

Abstract

The study is aimed at analyzing myeloprotective effect of new enterosorbents used separately and in combination with two recombinant granulocyte colony stimulating factors: Neupogen (Switzerland) and r-GCSF (Ukraine). The Ukrainian-made r-GCSF has been proved to be as therapeutically efficient as Neupogen (Switzerland); its combined use with C2 enterosorbent significantly increases myeloprotective effect of both GCSF versions.

References

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Published

2024-08-14

How to Cite

Todor, I., Lukianova, N., Rodionova, N., Shevchuk, O., Nikolaev, V., & Chekhun, V. (2024). Myeloprotective Effect of Combined Application of Ukrainian-Made Recombinant Granulocyte Colony Stimulating Factor (R-GCSF) and С2 Enterosorbent in Rats with Malignant Guerin Carcinoma. Science and Innovation, 11(2), 43–48. https://doi.org/10.15407/scine11.02.043

Issue

Vol. 11 No. 2 (2015): Science and Innovation

Section

Research and Engineering Innovative Projects of the National Academy of Sciences of Ukraine

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