Direct C-phosphorylation of 1-aryl- and 1-hetarylimidazoles by chlorides of phosphonic acids

Authors

  • A. V. Strizhak Taras Shevchenko National University of Kiev
  • I. V. Komarov Taras Shevchenko National University of Kiev
  • M.Yu. Kornilov Taras Shevchenko National University of Kiev
  • V.P. Khilya Taras Shevchenko National University of Kiev

DOI:

https://doi.org/10.15407/dopovidi2016.02.087

Keywords:

benzoimidazole, imidazole, phosphinamide, phosphinic acid, phosphorylation

Abstract

A convenient efficient method for the synthesis of 1-aryl- and 1-hetarylimidazole and benzoimidazole-2-ylphosphinic acids and their derivates has been proposed. Influence of a group at position 1 of imidazole on its reactivity towards phosphonic acids chlorides is investigated. It is shown that this method provides derivates with different substituents at an aryl or hetaryl ring. This method is a good alternative to the known methods of synthesis of such compounds.

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References

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Published

29.09.2024

How to Cite

Strizhak, A. V., Komarov, I. V., Kornilov, M., & Khilya, V. (2024). Direct C-phosphorylation of 1-aryl- and 1-hetarylimidazoles by chlorides of phosphonic acids . Reports of the National Academy of Sciences of Ukraine, (2), 87–95. https://doi.org/10.15407/dopovidi2016.02.087

Issue

No. 2 (2016): Reports of the National Academy of Sciences of Ukraine

Section

Chemistry

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