O- and N-glycosides of pyrazolo[3,4-c]isoquinoline. Synthesis and structural investigation by NMR

N.M. Bohdan; S.L. Bohza; D. Bousta; A.V. Grafov; O.I. Holembiovska; A.R. Khairulin; S.Yu. Suikov

doi:10.15407/dopovidi2026.01.040

Authors

N.M. Bohdan Institute of Organic Chemistry of the NAS of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0002-6522-1694
S.L. Bohza Institute of Organic Chemistry of the NAS of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0002-1274-3720
D. Bousta Faculty of Science Dhar El Mahraz, University Sidi Mohamed Ben Abdellah, Fes, Morocco https://orcid.org/0000-0001-6609-0094
A.V. Grafov Laboratory of Inorganic Chemistry, University of Helsinki, Helsinki, Finland https://orcid.org/0000-0002-7387-3676
O.I. Holembiovska National Technical University of Ukraine “Igor Sikorsky Kyiv Polytechnic Institute”, Kyiv, Ukraine https://orcid.org/0000-0001-5531-5374
A.R. Khairulin Taras Shevchenko National University of Kyiv, Kyiv, Ukraine https://orcid.org/0000-0003-4608-0838
S.Yu. Suikov Institute of Organic Chemistry of the NAS of Ukraine, Kyiv, Ukraine https://orcid.org/0000-0002-6556-3221

DOI:

https://doi.org/10.15407/dopovidi2026.01.040

Keywords:

pyrazolo[3,4-c]isoquinolines, glycosylation, correlation spectroscopy, N,O-glucosides, oxazoline.

Abstract

The synthetic potential of polyfunctional derivatives of the condensed system of pyrazolo[3,4-c] isoquinoline has been investigated. For the first time, a series of derivatives with a glucosamine fragment has been obtained and their spectral properties have been described.

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O- and N-glycosides of pyrazolo[3,4-c]isoquinoline. Synthesis and structural investigation by NMR

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