Pyranoneoflavonoids: synthesis and structure

Authors

  • V. S. Moskvina
  • D.Yu. Masich
  • V.P. Khilya

DOI:

https://doi.org/10.15407/dopovidi2014.12.122

Keywords:

pyranoneoflavonoids, structure, synthesis

Abstract

A convenient method for the synthesis of pyranoneoflavonoids by introducing a pyrane ring to the coumarin system has been proposed. A series of pyranoneoflavonoids and spiropyranoneoflavonoids of linear structure that are analogous to the naturally occurring graveolone has been obtained using ketones – acetone, ethylmethylketone, cyclopentanone, cyclohexanone, 2-methylcyclohexanone, 3-methylcyclohexanone, and 4-t-buthylcyclohexanone – in the Kabbe condensation. The structure of the obtained compounds has been studied.

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References

Murray R. D. H., Mendez J., Brown S. A. The natural coumarins – occurrence, chemistry and biochemistry, New York: Wiley, 1982.

Garazd M. M., Garazd Ya., L., Khilya V. P. Khimiya prirod. soedineniy, 2003, 39, No 1: 54–121 (in Russian).

Moskvina V. S., Khilya V. P., Khimiya prirod. soedinenii 2008, 44, No 1: 15–20 (in Russian).

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Panteleon V., Marakos P., Pouli N. et al. J. Pharm. Pharmacol., 2003, 55: P. 1029–1039. https://doi.org/10.1211/0022357021512

Published

19.03.2025

How to Cite

Moskvina, V. S., Masich, D., & Khilya, V. (2025). Pyranoneoflavonoids: synthesis and structure . Reports of the National Academy of Sciences of Ukraine, (6), 122–127. https://doi.org/10.15407/dopovidi2014.12.122