Purposeful Search and Constructing of New Medications (Rational Drug Design)

Authors

  • I.S. Chekman Bogomolets National Medical University, Kyiv
  • O.O. Kazakova Chuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine, Kyiv
  • A.O. Sirovaya Kharkiv National Medical University, Kharkiv
  • N.O. Gorchakova Bogomolets National Medical University, Kyiv
  • V.V. Patsko Bogomolets National Medical University, Kyiv

DOI:

https://doi.org/10.15407/visn2014.04.048

Keywords:

rational drug design, development of new medications, biological targets, computerized modeling of drugs

Abstract

This article is a review of methods and ways of searching and constructing of new medicines with using of modern computerized technologies. Types of methodic, which are divided by their key options, are also reviewed. Examples of using of rational drug design method and basic software programs, which are used by developers, are given. The short review of history of formation of the method is presented on this article as well.

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Published

2014-04-21