FRAGMENTATION OF SUCROSE MOLECULES UPON INTERACTION WITH ELECTRONS
DOI:
https://doi.org/10.15407/dopovidi2026.03.023Keywords:
monosaccharide, disaccharide, sucrose, fragmentation, mass spectrum, electron impact, appearance energies, fragment ionAbstract
The processes of sucrose molecule fragmentation during pair collisions with electrons were studied by mass spectrometry method. The mass spectrum of singly charged ions at an electron energy of 70 eV and a sucrose vapor temperature of 360 K consists of 12 groups of lines. For the first time, the threshold values — the ionization potential and the appearance energy of fragment ions — were experimentally measured during the interaction of electrons with sucrose molecules. The main pathways of sucrose molecule fragmentation leading to the formation of monovalent ions were experimentally studied and analyzed. The energies of formation of fragment ions upon dissociation of the excited parent ion of a sucrose molecule were estimated, and their dependence on the masses of fragment ions was analyzed. All data obtained for the sucrose molecule are compared with similar data for the related molecules fructose and glucose.
Downloads
References
Zavilopulo, A. N., Bulhakova, A. I., Demes, S. S., Remeta, E. Yu. & Vasiliev, A. V. (2021). Ionization and fragmentation of valine molecules in the gas phase by electron impact. Eur. Phys. J. D, 75, 287. https://doi.org/10.1140/epjd/s10053-021-00294-2
Gao, Y., Bu, J., Peng, Z. & Yang, B. (2014). Radical reactions in the gas phase: recent development and application in biomolecules. J. Spectrosc., 570863. https://doi.org/10.1155/2014/570863
Baccarelli, I., Bald, I., Gianturco, F. A., Illenberger, E. & Kopyra, J. (2011). Electron-induced damage of DNA and its components: Experiments and theoretical models. Phys. Rep., 508, pp. 1-44. https://doi.org/10.1016/j.physrep.2011.06.004
Sanche, L. (2005). Low energy electron-driven damage in biomolecules. Eur. Phys. J. D., 35, pp. 367-390. https://doi.org/10.1140/epjd/e2005-00206-6
Winstead, C. & McKoy, V. (2012). Low-energy electron collisions with biomolecules. J. Phys.: Conf. Ser., 388, 012017. https://doi.org/10.1088/1742-6596/388/1/012017
Ghosh, D., Golan, A., Takahashi, L. K., Krylov, A. I. & Ahmed, M. (2012). A VUV photoionization and ab initio determination of the ionization energy of a gas-phase sugar (deoxyribose). J. Phys. Chem. Lett., 3, No. 1, pp. 97-101. https://doi.org/10.1021/jz201446r
Vall-llosera, G., Huels, M. A., Coreno, M., Kivimäki, A., Jakubowska, K., Stankiewicz, M. & Rachlew, E. (2008). Photofragmentation of 2-deoxy-D-ribose molecules in the gas phase. ChemPhysChem, 9, No. 7, pp. 1020-1029. https://doi.org/10.1002/cphc.200700635
Keller, A., Kopyra, J., Gothelf, K. V. & Bald, I. (2013). Electron-induced damage of biotin studied in the gas phase and in the condensed phase at a single-molecule level. New J. Phys., 15, 083045. https://doi.org/10.1088/1367-2630/15/8/083045
Baccarelli, I., Gianturco, F.A., Scifoni, E., Solov’yov, A. V., Surdutovich, E. (2010). Molecular level assessments of radiation biodamage. Eur. Phys. J. D, 60, pp. 1-10. https://doi.org/10.1140/epjd/e2010-00216-3
Ptasińska, S., Denifl, S., Scheier, P. & Märk, T. D. (2004). Inelastic electron interaction (attachment/ionization) with deoxyribose. J. Chem. Phys., 120, No. 18, pp. 8505-8511. https://doi.org/10.1063/1.1690231
Kim, Y.-K. & Rudd, M. E. (1994). Binary-encounter-dipole model for electron-impact ionization. Phys. Rev. A, 50, No. 5, pp. 3954-3967. https://doi.org/10.1103/physreva.50.3954
Taylor, V. F., March, R. E., Longerich, H. P. & Stadey, C. J. (2005). A mass spectrometric study of glucose, sucrose, and fructose using an inductively coupled plasma and electrospray ionization. Int. J. Mass Spectrom., 243, No. 1, pp. 71-84. https://doi.org/10.1016/j.ijms.2005.01.001
Bandurin, Yu. A., Popik, T. Yu. & Zavilopulo, A. M. (2022). Interaction of photons with glucose and fructose molecules. Dopov. Nac. akad. nauk Ukr., No. 1, pp. 58-63 (in Ukranian). https://doi.org/10.15407/dopovidi2022.01.058
Demes, S., Zavilopulo, A. & Remeta, E. (2023). Ionization of glucose and ribose molecules by electron impact. Eur. Phys. J. D, 77, 187. https://doi.org/10.1140/epjd/s10053-023-00766-7
Shpenik, O. B., Zavilopulo, A. N., Agafonova, A. S. & Romanova, L. G. (2008). Mass spectrometry dosage of glucose molecules. Dopov. Naс. acad. nauk Ukr., No. 5, рр. 96-101 (in Ukranian).
Spectral Database for Organic Compounds SDBS. Retrieved from https://sdbs.db.aist.go.jp/SearchResult.aspx
Frolov, A., Hoffmann, P. & Hoffmann, R. (2006). Fragmentation behavior of glycated peptides derived from D-glucose, D-fructose and D-ribose in tandem mass spectrometry. J. Mass Spectrom., 41, No. 11, pp. 1459-1469. https://doi.org/10.1002/jms.1117
McMurry, J. E. (2010). Fundamentals of organic chemistry. 7th ed. Belmont: Cengage Learning.
Cline, G. W. & Shulman, G. I. (1995). Mass and positional isotopomer analysis of glucose metabolism in periportal and pericentral hepatocytes. J. Biol. Chem., 270, No. 47, pp. 28062-28067.
Bandurin, Yu. A., Zavilopulo, A. M., Remeta, E. Yu. & Vizenko, M. P. (2023). Mass spectroscopic studies of glucose after neutron irradiation. Reports of the Dopov. Naс. acad. nauk Ukr., No. 5, pp. 9-16 (in Ukranian). https://doi.org/10.15407/dopovidi2023.05.009
Zavilopulo A. M. & Remeta E. Yu. (2024). Ionization of fructose molecules by electron impact. Dopov. Naс. acad. nauk Ukr., No. 4, pp. 24-32 (in Ukranian). https://doi.org/10.15407/dopovidi2024.04.024
Zavilopulo, A. N., Shpenik, O. B., Mylymko, A. N. & Shpenik, V. Yu. (2019). Mass spectrometry of D-ribose molecules. Int. J. Mass Spectrom., 441, pp. 1-7. https://doi.org/10.1016/j.ijms.2019.03.008
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Reports of the National Academy of Sciences of Ukraine
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
