Aspects of the creation of neuroprotective antiinflammatory drugs

Authors

  • I.S. Chekman PHEI Kyiv Medical University
  • I.F. Belenichev Zaporizhzhya State Medical University
  • A.O. Syrovaja Kharkiv National Medical University
  • N.A. Gorchakova Bogomolets National Medical University, Kyiv
  • N.V. Buhtijarova Zaporizhzhya State Medical University
  • V.P. Ryzhenko Zaporizhzhya State Medical University
  • O.L. Levashova Kharkiv National Medical University
  • N.N. Chalenko Kharkiv National Medical University

DOI:

https://doi.org/10.15407/dopovidi2019.09.088

Keywords:

antiinflammatory antioxidant properties, computer programs, neuroprotective, quantum- chemical investigations, virtual screening

Abstract

The chemical, physiological, and pharmacological aspects of creation of neuroprotective antiinflammatory drugs are considered. It is stated the expediency of the creation of neuroprotective compounds among the 1,2,4- tri azol derivatives and antiinflammatory compounds as the coxibes derivatives. During the synthesis of new compounds, computer programs, quantum-chemical investigations, and virtual screening have been used to determine antioxidant properties.

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References

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Published

24.04.2024

How to Cite

Chekman, I., Belenichev, I., Syrovaja, A., Gorchakova, N., Buhtijarova, N., Ryzhenko, V., Levashova, O., & Chalenko, N. (2024). Aspects of the creation of neuroprotective antiinflammatory drugs . Reports of the National Academy of Sciences of Ukraine, (9), 88–98. https://doi.org/10.15407/dopovidi2019.09.088