Application of analogs of gonadotropinum-releasing hormone to girls with spontaneous sexual development, who suffer from the patients with Shereshevskii–Terner syndrome
DOI:
https://doi.org/10.15407/dopovidi2014.10.175Keywords:
gonadotropinum-releasing hormone, sexual development, Shereshevskii–Terner syndromeAbstract
This article presents the results of research on the assessment and the treatment of 70 children with Turner's syndrome. 38 girls had classic version karyotype — 45, XO and 32 children — mosaic forms. At 8 children from them, sexual development began without medicamental intervention. It is proved that the use of analogues of gonadotropin-releasing hormone in combination with growth hormone significantly improves the ultimate height of patients with independent activation of ovaries.
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Dedov I. I., Peterkova V. A., Volevodz N. N. Shereshevskoho Syndrome Turner (pathogenesis, Clinic, Diagnosis, Treatment): Methodical recommendations, Moscow: GUENTS RAMN, 2009 (in Russian).
Bondy C. A. J. Clin. Endocrin. Metab., 2006, 10: 1310–1374.
Saenger P. N. Engl. J. Med., 1996, 335: 1749–1754. https://doi.org/10.1056/NEJM199612053352307
Sybert V. P., McCauley E. N. Engl. J. Med., 2004, 351: 1227–1238. https://doi.org/10.1056/NEJMra030360
Dedov I. I., Semicheva T. V., Peterkova V. A. Sexual development of children: norm and pathology, Moscow: Kolor It Studio, 2002 (in Russian).
Ranke M. B. et al. Acta Paediatr. Scand, 1988, 343: 22–30.
Donaldson M. D. C. et al. Arch. Dis. Child., 2006, 91: 513–520. https://doi.org/10.1136/adc.2003.035907
Sas T. C., de Muinck Keizer-Schrama S. M. Horm. Res., 2001, 56, No 1: 38–43.
Gravholt C. H. Expert. Opin. Pharmacother, 2001, 10, No 2: 1633–1647. https://doi.org/10.1517/14656566.2.10.1633
Hanton L. et al. J. Womens Health, 2003, 12: 971–977. https://doi.org/10.1089/154099903322643893
Tsuchiya K. et al. Am. J. Hum. Genet., 1995, 57: 1400–1407.
Gravhholt C. H. Europ. J. Endocrinol, 2004, 151: 657–687. https://doi.org/10.1530/eje.0.1510657
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