Development and researches of a biological active polymeric material with immobilized Vincristine
DOI:
https://doi.org/10.15407/dopovidi2014.05.121Keywords:
biological active, immobilized Vincristine, polymerAbstract
New composite materials on the basis of branched out polyether glycol urethane (PEGU) with physically immobilized antineoplastic preparation Vincristine are developed, and their efficiencies are investigated. The method of IR-spectroscopy established the influence of Vincristine on the structure of the received composites. By results of physical-mechanical tests, the introduction of Vincristine into the structure of PEGU doesn't lead to a deterioration of its physical-mechanical properties, and its high elasticity and tensile strength are conserved. The obtained film material can be recommended for the passing of further medical-biological tests as a material for the production of covers of hydrophilic implants.
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