Solid-phase microextraction of aliphatic aldehydes C5–C8 and gas chromatographic determination for lung cancer diagnosis

Authors

  • I. B. Zakharkiv Taras Shevchenko National University of Kiev
  • M. F. Zui Taras Shevchenko National University of Kiev

DOI:

https://doi.org/10.15407/dopovidi2016.08.085

Keywords:

aliphatic aldehydes, derivatization, gas chromatography, o-(2;3;4;5;6-pentafluorobenzyl) hydroxylamine hydrochloride, solid phase microextraction

Abstract

A headspace solid-phase microextraction procedure followed by gas chromatography with flame ionization detection has been developed for the preconcentration and the determination of aliphatic aldehydes C5−C8 in the form of its o-(2,3,4,5,6-pentafluorobenzyl)hydroxylamine derivatives in water samples. Commercial polydimethylsiloxane-divinylbenzene fiber was used as a preconcentration coating. Under optimal conditions, the enrichment factors of analytes were in the range 7280–8650, and the limits of detection were 0.016–0.020 μM/L.

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References

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Published

15.11.2024

How to Cite

Zakharkiv, I. B., & Zui, M. F. (2024). Solid-phase microextraction of aliphatic aldehydes C5–C8 and gas chromatographic determination for lung cancer diagnosis . Reports of the National Academy of Sciences of Ukraine, (8), 85–91. https://doi.org/10.15407/dopovidi2016.08.085

Issue

No. 8 (2016): Reports of the National Academy of Sciences of Ukraine

Section

Chemistry

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