Spectroscopic markers of biological molecules and their application in biotechnology and medicine: status and prospects

Transcript of scientific report at the meeting of the Presidium of NAS of Ukraine, May 31, 2023

Authors

DOI:

https://doi.org/10.15407/visn2023.08.069

Abstract

The report presents the results of experimental and theoretical research carried out at the Institute of Physics of the NAS of Ukraine to investigate, using spectral analysis and numerical modeling methods, the physical mechanisms of the functioning of various biological macromolecules (proteins, nucleic acids, lipids), supramolecular nanoscale biological systems (biological membranes) and nanostructures (nanostructured surfaces and nanoparticles) containing biological molecules.

References

Panteleichuk A.B., Kadzhaya N.V., Shmeleva A.A., Malysheva T.A., Gnatyuk O.P., Dovbeshko G.I. Theoretical substantiation of the efficiency of biopolymers application in experimental TBI (literature review and own results). Ukrainian Neurosurgical Journal. 2019. 25(4): 64—71. https://doi.org/10.25305/unj.184031

Panteleichuk A., Kadzhaya M., Biloschytsky V., Shmeleva A., Petriv T., Gnatyuk O., Dovbeshko G., Kozakevych R., Tyortyh V. Composite chitosan/polyethylene oxide film for duraplasty in traumatic brain injury model in rats. Cell and Organ Transplantology. 2020. 8(1): 26—31. https://doi.org/10.22494/cot.v8i1.105

Kolesnik L., Pyaskovskaya O.N., Gnatyuk O.P., Cherepanov V.V., Karakhim S.O., Polovii I.O., Posudievsky O.Yu., Konoshchuk N.V., Strelchuk V.V., Nikolenko A.S., Dovbeshko G.I., Solyanik G.I. The effect of 2D tungsten disulfide nanoparticles on Lewis lung carcinoma cells in vitro. RSC Advances. 2021. 11(27): 16142—16150. https://doi.org/10.1039/D1RA01469B

Gnatyuk O.P., Dovbeshko G.I., Yershov A., Karakhim S.O., Ilchenko O., Posudievsky O.Yu. 2D-BN nanoparticles as a spectroscopic marker and drug delivery system with protection properties. RSC Advances. 2018. 8(53): 30404—30411. https://doi.org/10.1039/C8RA05085F

Krisanova N., Pozdnyakova N., Pastukhov A., Dudarenko M., Shatursky O., Gnatyuk O., Afonina U., Pyrshev K., Dovbeshko G., Yesylevskyy S., Borisova T. Amphiphilic anti-SARS-CoV-2 drug remdesivir incorporates into the lipid bilayer and nerve terminal membranes influencing excitatory and inhibitory neurotransmission. Biochimica et Biophysica Acta (BBA) — Biomembranes. 2022. 1864(8): 183945. https://doi.org/10.1016/j.bbamem.2022.183945

Gnatyuk O.P., Afonina U.K., Krisanova N., Pozdnyakova N., Borisova T.O., Karakhim S.O., Dovbeshko G.I. Spectroscopic signatures of synaptosomes: ATR-IR spectroscopy study. Molecular Crystals and Liquid Crystals. 2022. 749(1): 25—32. https://doi.org/10.1080/15421406.2022.2067672

Published

2023-08-22

How to Cite

Dovbeshko, G. I. (2023). Spectroscopic markers of biological molecules and their application in biotechnology and medicine: status and prospects: Transcript of scientific report at the meeting of the Presidium of NAS of Ukraine, May 31, 2023. Visnyk of the National Academy of Sciences of Ukraine, (8), 69–73. https://doi.org/10.15407/visn2023.08.069