Construction of the Overproducers and Development of Technology for Flavin Mononucleotide Production Based on Yeast Candida famata
DOI:
https://doi.org/10.15407/scin8.05.078Keywords:
flavin mononucleotide (FMN), yeast, Candida famata, oversynthesis, overproducers.Abstract
The strains of the yeast Candida famata containing 5-6 copies of FMN1 gene (encoding riboflavin kinase) were constructed. The optimal conditions for flavin mononucleotide (FMN) synthesis under batсh and feed-batсh cultivation were investigated. The medium components and cultivation conditions for maximal accumulation of product – FMN were optimized.
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